A highlight of the Gallery's German art collection is its holding of sixteenth-century panel paintings. Among the works are striking portraits by Wolf Huber, Conrad Faber, Bernhard Strigel and Georg Pencz, as well as religious subjects from the workshop of Lucas Cranach, a key figure in the German Renaissance. The Gallery possesses a fine eighteenth-century portrait of the Irishman Thomas Connolly, which was painted in Rome by Anton Raphael Mengs.
The collection holds early twentieth-century paintings by the German Expressionist artists Emil Nolde, Max Pechstein and Gabriele Münter. In 2008 the Gallery acquired Umpferstedt III (1919) by the German-American artist Lyonel Feininger; this composition relates to his important design for the first cover of the Bauhaus manifesto.